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In courts across the UK, blood alcohol testing is an essential part of the evidential picture, providing an insight into an individual’s alcohol consumption.

In cases where the safeguarding of children and vulnerable people is paramount, such tests provide a rich source of information, enabling counsel, family law professionals and social workers to act on urgent welfare needs.  

But when it comes to blood alcohol tests, Phosphatidylethanol (PEth) testing provides by far the most conclusive insight into a person’s drinking patterns.

Here, we breakdown everything you need to know about PEth testing and how it can work alongside hair alcohol testing to provide a full picture of alcohol consumption for legal cases.

PEth alcohol testing – what makes it so conclusive?

There are four main types of blood alcohol testing that we carry out at AlphaBiolabs, as part of our legal alcohol testing service, all of which can provide a four-week historic overview of alcohol use:

  • Phosphatidylethanol (PEth) – a direct biomarker of alcohol
  • Carbohydrate Deficient Transferrin (CDT)
  • Liver Function Test (LFT)
  • Mean Corpuscular Volume (MCV)

Unlike CDT, LFT and MCV – all of which are indirect biomarkers of alcohol and whose presence can be affected by pre-existing medical conditions and medications, among other factors – PEth is a direct biomarker of alcohol.

This means that it is only present in the body when alcohol has been consumed.

An abnormal phospholipid, it requires ethanol for its production. PEth production begins as soon as ethanol is consumed and accumulates in the blood with frequent alcohol consumption, giving it a high specificity (48-89 per cent) and sensitivity (88-100 per cent).

Drinking experiments show that PEth can be detected in blood after one to two hours, and for up to 12 days after a single drinking episode. In addition, daily alcohol consumption of more than 60g of ethanol (7.5 units) can clearly be distinguished from lower alcohol consumption.

As such, PEth testing can detect chronic and single-drinking episodes. 

The conclusiveness of a PEth test and the wealth of information it provides is what makes it the most essential of all blood alcohol tests, allowing us to monitor abstinence, drinking behaviour, or identify relapse. PEth analysis is also the only blood alcohol test that can be undertaken during pregnancy or within two months of the birth.

In fact, AlphaBiolabs sales data shows that recognition for the value of PEth testing is on the rise, with sales of such tests having more than doubled year-on-year among the legal profession (2020-21).  

PEth testing vs hair alcohol testing

PEth is second only to the detection of ethyl glucuronide (EtG) and ethyl palmitate (EtPa), a fatty acid ethyl ester (FAEE), in the hair.

Both EtG and EtPa are direct biomarkers of alcohol and give a highly accurate insight into patterns of drinking, with a three- or six-month overview of usage. Each is absorbed into the hair via different routes, and their levels can assist in assessing excessive alcohol consumption.

EtG is water soluble, produced in the liver and can be impacted by various hair treatments including excessive washing. EtPa is formed in the sebaceous glands from ethanol diffusing from the blood circulation and then deposited into hair primarily from sebum (from the oil glands on the scalp).

EtPa (a type of FAEE) is lipophilic so while not water soluble, its presence can be affected using alcohol-containing hair products such as sprays, gels, and wax.

Because of their respective strengths and weaknesses, both EtG and EtPA tests should be performed, and their findings used to support each other, as shown in LB Richmond v B & W & B & CB [2010] EWHC (2903) Fam, where Mr Justice Moylan gave guidance on the evidential worth of hair strand testing.

Within his guidance, it was also stressed that hair strand tests should not be used in isolation to reach evidential conclusions.

By performing these tests alongside PEth and other blood tests, a more holistic conclusion can be drawn as to a person’s alcohol use.

Getting the full picture

There is no getting around the fact that blood alcohol testing combined with hair testing provides us with the fullest picture from which to draw conclusions.

This is especially important in family cases, where safeguarding children and vulnerable people is the highest priority.

Using highly accurate scientific analysis and examining the way in which the body absorbs alcohol, a case can be made to protect those in need – and reunite families where abstinence has been achieved. 

AlphaBiolabs works with family law professionals and local authorities across the UK, providing a range of legal testing services including blood alcohol testing and hair alcohol testing.

Legal clients can claim 20 per cent off all AlphaBiolabs blood alcohol tests until 28th February 2022 by quoting ALC20 when placing an order.

For every legal instruction received throughout 2022, we will also be donating £5 via our Giving Back campaign to support four incredible charities that work with vulnerable children and families across the UK.

For more information or to place an order, call our Customer Services team on 0330 600 1300 or email testing@alphabiolabs.com, and a member of the legal sales team will be in touch.